Flora Migranon II Butterbur Extract - Contains Petadolex®, an extract made from organically grown butterbur and carefully prepared to ensure that it is safe and that only the beneficial active constituents of the plant are captured. In its natural state, butterbur contains toxic compounds called pyrrolizidine alkaloids (PAs) that can be damaging to the body, but the butterbur in Flora’s Migranon II has undergone a patented CO2 extraction method that removes the PAs while guaranteeing therapeutic levels of the key active substances, petasin and isopetasin.