Natural Factors Mega Probiotic Powder - 12 billion active cells. Three strains of lactobacillus bacteria support the health of the small intestine, and one strain of bifidobacterium supports the health of the large intestine. Probiotics have been shown to play an important role in preventing or controlling diarrhea, constipation and other digestive disorders, dental cavities, bacterial vaginosis, and allergies. Enteric coating is not required for all probiotic strains. With regards to stomach acid resistance, not all strains are created equal. Natural Factors has carefully selected naturally acid-resistant strains so they may be consumed at any time, with or without meals, and are safely delivered to the intestine unharmed.