New Roots Indole-3-Carbinol - Indole-3-carbinol is a potent antioxidant which helps reduce oxidative stress exerted by free radicals. It also supports estrogen metabolism. Indole-3-carbinol (I3C) is the phytochemical responsible for the antioxidant properties of the family of vegetables known as Brassicaceae (formerly Cruciferae), which includes broccoli, cabbage, Brussels sprouts, kale, and cauliflower. Indole-3-carbinol is an organic compound formed as a result of the action of the enzyme myrosinase with the precursor compound indole-3-glucosinolate within these vegetables upon maceration (crushing). The antioxidant activity of indole-3-carbinol protects cells, including their DNA, from the effects of environmental toxins we are exposed to on a daily basis.